The early-onset periodontitis may be associated with micronutrient abnormalities including Vitamin D deficiency suggests a case reported by researchers and the same has been published in the Medicine.
Periodontitis is an inflammatory disease with multifactorial etiology. Vitamin D, a fat-soluble vitamin, has protective effects on inflammatory response in various systemic conditions. The clinical features of vitamin D deficiency include growth failure, hypotonia, pathologic fractures, rachitic rosary, tetany and so on. Here we present a case of 12-year-old girl affected by early-onset periodontitis accompanied with vitamin D deficiency.

According to the history, a 12-year-old girl reported with gingival redness, bleeding associated with tooth brushing, and mandibular anterior teeth movement, with difficulty in mastication for the past 2 months to the attending doctors. There is no relevant family history or special systemic disease history. The serological microelement test showed vitamin D levels were significantly lower than normal range. Also Immunological test showed abnormal CD4+/CD8+(CD3+CD4+/CD3+CD8+) ratio as well.
Based on the clinical and serological findings, this patient was ultimately diagnosed with early-onset periodontitis accompanied with vitamin D deficiency.
The main treatments for this patient were 3-fold: periodontal therapy, vitamin D supplement and oral hygiene instructions. Following 1-year therapy, periodontal conditions recovered and became stable. And serological vitamin D levels returned to normal range.
The case of interest serves as an important reminder to clinicians, that the early-onset periodontitis may be associated with micronutrients abnormalities, and early-diagnosis and treatment could avoid the body heathy disorders.
Reference:
Li, Chen PhDa; Zhang, Jinmei PhDa; Wang, Lufei PhDb; Yang, Jingmei PhDa,*. A case of early-onset periodontitis with vitamin D deficiency: A case report and literature review. Medicine 102(39):p e35321, September 29, 2023. | DOI: 10.1097/MD.0000000000035321
Keywords:
Li, Chen PhDa; Zhang, Jinmei PhDa; Wang, Lufei PhDb; Yang, Jingmei, case, early-onset, periodontitis, vitamin D deficiency, case report, literature review, Medicine