November 06, 2025

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Ultrasound Guidance Improves Results Of Arthrocentesis Of Medium-Sized Joint Effusions: Study

Ultrasound-Guided vs. Landmark-Guided Arthrocentesis

Ultrasound-Guided vs. Landmark-Guided Arthrocentesis

Ultrasound-guided (USG) is better than landmark-guided (LMG) medium-sized joint arthrocentesis, according to a recent study published in the Academic Emergency Medicine.

Joint and soft tissue injections are frequent procedures in rheumatological practice, but it is recognised that the success rate with which injections reach their intended target using anatomical landmarks as guidance is limited.1 High-resolution ultrasound (US) is a valid, "bed-side" imaging technique,2 which is increasingly used in rheumatological practice for diagnostic purposes, but also as image guidance for needle arthrocentesis to perform aspirations, injections, or synovial biopsies.

Arthrocentesis is commonly performed in the emergency department, but success rates vary based on location. Presently, there is a paucity of data assessing the utility of ultrasound-guided (USG) medium-sized joint arthrocentesis. The objective of this study was to compare the success of USG and landmark-guided (LMG) medium-sized joint arthrocentesis.

This was a single-centre, prospective, randomized clinical trial (NCT03327584) of a convenience sample of adult patients who presented to an urban, university hospital with over 105,000 visits annually. Patients with a suspected medium-sized joint effusion (defined as elbow, wrist, or ankle) undergoing arthrocentesis were randomized into LMG or USG using the GE Logiq e linear transducer (4–10 MHz). The following patients were excluded: on anticoagulation, with soft tissue infection overlying the joint, or involving an artificial joint. Statistical analysis included the Fisher exact, Mann-Whitney U-test, and t-test.

Results

Overall, 44 patients were enrolled with 23 patients randomized into the LMG group and 21 patients into the USG arm. USG was significantly better than LMG with an overall success of 94.1% versus 60% for LMG (difference = 34.1%, 95% confidence interval [CI] = 4.90 to 58.83). USG first-pass success was 82.4% versus 46.7% for LMG (difference = 35.7%, 95% CI = 2.76 to 60.37) and a mean of 1.35 attempts versus 2.00 for LMG (difference = 0.65, 95% CI = 0.005 to 1.296). Of the 14 LMG failures, eight had no effusion present on USG crossover. Four patients in the USG group had no effusion present.

Thus, ultrasound guidance improved first-pass and overall successful arthrocentesis of medium-sized joint effusions.

Reference

Ultrasound-versus landmark-guided medium-sized joint arthrocentesis: A randomized clinical trial by Ryan C. Gibbons et al. published in the Academic Emergency Medicine. Read the full study

Keywords

  • Academic Emergency Medicine
  • Ultrasound
  • Landmark-guided
  • Medium-sized joint arthrocentesis
  • Arthrocentesis
  • Ryan C. Gibbons
  • Allison Zanaboni
  • Jessica Genninger
  • Thomas G. Costantino

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