November 05, 2025

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TCA Paint Effective In Treatment Of Boxcar & Polymorphic Acne Scars

Scarring is a common complication of acne vulgaris with a significant impact on the psychological well-being of patients. While laser resurfacing remains the most effective treatment option for atrophic acne scars, the high incidence of post-treatment adverse effects limits its use. In a study, researchers have reported that trichloroacetic acid (TCA) is safe and effective in treating boxcar and polymorphic scars. The study findings were published in the journal Dermatological Surgery on December 16, 2021.
Acne vulgaris is a common disorder in the adolescent age group and unfortunately, post acne facial scarring is common. Previous studies demonstrated that trichloroacetic acid is efficacious in treating ice-pick scars, but the utility in other scar types is understudied. However, treatment options targeting both boxcar and polymorphic scars are still lacking. Therefore, Dr Cong Sun and Dr David Lim conducted a study to evaluate the efficacy and safety of 90% TCA in a boxcar and polymorphic acne scars using a novel brush applicator.
In a prospective study, the researchers included forty-one patients with acne scars. They treated the patient's boxcar and polymorphic scar with 90% TCA applied with a cosmetic brush. Each patient received three treatment sessions spaced between 7 and 9 weeks apart.
Key findings of the study:
Upon analysis, the researcher found that all participants had good to excellent outcomes as per Jacob and colleagues' grading.
They noted that the patients with skin Type 3 to 6 had more excellent outcomes (13 patients, 59%) than patients of skin type 1 to 2 (9 patients, 41%).
They reported two (5%) post-procedural complications.
They further mentioned that five participants (14%) were on concomitant isotretinoin with no appreciable increase in reepithelialization time or rate of complications.
The authors concluded, "Focal 90% TCA with a cosmetic brush applicator is safe and effective in treating boxcar and polymorphic scars. The clinical outcome is good to excellent with low rates of complication."
For further information:
DOI: 10.1097/DSS.0000000000003339

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