Caries is a dynamic dental hard tissue disease caused by interaction between specific oral bacteria and diet that damages the enamel or dentin surface, resulting in demineralization. In a new study researchers embarked to determine the effect of rice husk nanosilica on the increase in dentin hydroxyapatite and its antimicrobial effects against Streptococcus mutans and a possible treatment option for caries.

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Rice husk nanosilica can induce the formation of dentin hydroxyapatite and has antimicrobial effects suggests a recent study published in the European Journal of Dentistry
Rice husk nanosilica has a porous, amorphous structure with a silica (SiO2) surface. Silica interacts with calcium ions to form hydroxyapatite and can induce the formation of reactive oxygen species (ROS), which harm microorganisms. This research determines the effect of rice husk nanosilica on the increase in dentin hydroxyapatite and its antimicrobial effects against Streptococcus mutans. Researchers divided 27 dental cavity samples into three groups (n = 9). Group 1: normal dentin, Group 2: demineralized dentin, Group 3: demineralized dentin treated with rice husk nanosilica. The samples were analyzed using X-ray diffraction (XRD) to evaluate the formation of dentin hydroxyapatite. To analyze the viability of S. mutans after exposure to 2% nanosilica rice husk, we conducted an antimicrobial MTT assay. The Kruskal–Wallis test evaluates the formation of dentin hydroxyapatite, and the t-test evaluates the viability of S. mutans.
There was an increase in the amount of dentin hydroxyapatite after the application of rice husk nanosilica compared with the control group (normal dentin), and 2% rice husk nanosilica had an antimicrobial effect (p < 0.005) in the group exposed to it.
Researchers concluded that Rice husk nanosilica can remineralize dentin by forming hydroxyapatite and has an antimicrobial effect with a marked decrease in viability of S. mutans
Reference:
Iffi Aprillia , Sylva Dinie Alinda , Endang Suprastiwi. Efficacy of Rice Husk Nanosilica as A Caries Treatment (Dentin Hydroxyapatite and Antimicrobial Analysis).
CC BY 4.0 · Eur J Dent 2022; 16(04): 875-879
DOI: 10.1055/s-0041-1741373