Rare Case Of Asymptomatic Huge Primary Retroperitoneal Pseudocyst Reported
- byDoctor News Daily Team
- 16 July, 2025
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A rare case report aimed to present a patient and to check all the available literature on this kind of rare disease, was published in the BMC surgery.
Retroperitoneal non-pancreatic or idiopathic pseudocysts are very rare lesions. The retro-peritoneum is a space situated behind the parietal peritoneum and in front of the transversalis fascia. The retroperitoneum consists of three parts: the anterior pararenal space, the perirenal space, and the posterior pararenal space. The anterior pararenal space contains pancreas, 2nd to 4th parts of the duodenum, and the ascending and descending colon. The perirenal space contains the kidneys, proximal ureters, adrenal glands, and perirenal fat. The posterior pararenal space contains fat tissue and join inferiorly to the pelvic extraperitoneal space.
Most of the retroperitoneal masses originate from the retroperitoneal organs and are not considered as the primary retroperitoneal masses. A primary retroperitoneal mass is diagnosed once the location is inside the retroperitoneal space and after exclusion of the originity from an organ. Primary retroperitoneal masses can be divided into solid and cystic groups and these two groups can be classified as neoplastic and non-neoplastic subgroups. Table 1 shows the differential diagnosis of the primary retroperitoneal masses
A patient who was a 67-year-old Iranian man admitted with mild abdominal discomfort for three months. Ultrasonography and CT scan revealed a huge cystic structure within the retroperitoneal space. The lesion was excised through midline laparotomy and opening of the retro-peritoneum. The histopathology of the cyst wall revealed a benign cystic lesion with no epithelial lining. A histologic diagnosis of non-neoplastic retroperitoneal pseudocyst was made.
Thus, researchers concluded that the primary non-pancreatic retroperitoneal pseudocysts are rare lesions and have to be distinguished from other differential diagnoses of retroperitoneal lesions, and a surgeon should be aware of the possible occurrence of these lesions with unknown origin. Surgical excision is the only way to exclude malignancy and confirm the diagnosis.
Reference:
An asymptomatic huge primary retroperitoneal pseudocyst: a case report and review of the literature by Lotfolah Abedini, et al. published in the BMC Surgery.
https://bmcsurg.biomedcentral.com/articles/10.1186/s12893-022-01510-5
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