Patients with ulcer and mechanical stimulation may have a high risk of experiencing recurrent epulis suggests a recent study published in The Journal of the American Dental Association
The word epulis is a generic term that refers to a growth on the gingiva or alveolar mucosa. However, the best-known usage of this term is in epulis fissuratum, which is a reactive overgrowth of fibrous connective tissue in response to an ill-fitting denture. The association between clinicopathologic characteristics and the relapse of fibrous gingival hyperplasia is unknown.

The records of 211 consecutive patients with a clinicopathologic diagnosis of fibrous gingival hyperplasia were retrieved. Patients who experienced relapse after surgical excision of the lesion were considered case patients (n = 30). All control patients were informed that there was no recurrence (n = 181). Logistic regression was used to evaluate the associations among different characteristics and the recurrence. Stratified analyses on sex was applied to identify the different associations.
Results
Binary logistic regression showed that patients with ulcer or mechanical stimulation had a higher risk of experiencing recurrence.
Stratified analysis of sex identified significant association in females
No significant difference was observed in males
Male patients with larger epulides had fewer recurrence
There was no significant difference in pathologic calcification between case and control patients (P > .05).
Patients with ulcer and mechanical stimulation may have a high risk of experiencing recurrent epulis. More attention should be paid to patients with ulcer and mechanical stimulation. Apart from complete surgical removal, it is important to remove local stimulation to prevent recurrence of these lesions.
Reference:
Kehui Xu, Yifei Zhu, Yuanyuan Li, Franklin R. Tay, Kai Jiao, Lina Niu. Clinical and pathologic factors associated with the relapse of fibrous gingival hyperplasia. The Journal of the American Dental Association Published:October 25, 2022DOI:https://doi.org/10.1016/j.adaj.2022.08.014
Key Words
Gingival diseases, fibrous epulis, recurrence, Kehui Xu, Yifei Zhu, Yuanyuan Li, Franklin R. Tay, Kai Jiao, Lina Niu, The Journal of the American Dental Association