November 04, 2025

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Nephroscopy Versus Cystoscopy For Bladder Stones Significantly Lowers Operative Time: Study

China: Although advancements in contemporary antibiotic treatment and diet have lowered the prevalence of bladder stones (BSs) in recent decades, BSs remain the most prevalent kind of stone in the lower urinary tract, accounting for 5 percent of all urinary calculi. According to a new study, both nephroscopy and cystoscopy had good stone removal efficiency, low complication rates, and short hospitalizations. The mean urethral entry for big stone fragments varies depending on the treatment strategy.
This study was conducted by Liping Gou and the team with the objective to examine the safety and efficacy of nephroscopy and cystoscopy in transurethral cystolithotripsy (TUCL) for bladder stones. The findings of this study were published in BMC Surgery.
For the following research Up to January 2021, the PubMed, Web of Science, Embase, EBSCO, and Cochrane Library databases were searched for research evaluating the effect of different kinds of endoscopes on patients undergoing TUCL. The PRISMA statement was followed throughout the search strategy and research selection procedure.
The results of this study stated as follows:
1. The meta-analysis comprised five randomized controlled trials. The findings revealed no difference in stone-free rate (RR = 1.00) between the two groups, as well as nonsignificant heterogeneity (I2 = 0%), and all patients were stone-free.
2. When compared to the cystoscope group, the use of the nephroscope considerably reduced operation time (RR= 26.26), and there was considerable heterogeneity (I2= 87%).
3. There was no significant difference between the two groups in mean urethral entry (RR = 0.66), hospitalization (MD = 0.08), or overall complication rate (RR=1.37).
In conclusion, according to this comprehensive study, both nephroscopy and cystoscopy have a high efficiency of stone removal, a low risk of complications, and a short hospital stay. The mean urethral entry for big stone fragments varies depending on the treatment strategy. The use of nephroscopy, on the other hand, can drastically minimize operational time.
Reference:
Gou, L., Wang, Z., Zhou, Y. et al. Comparison of nephroscopy and cystoscopy used in the treatment of bladder stones: a systematic review and meta-analysis of randomized controlled trials. BMC Surg 21, 448 (2021). https://doi.org/10.1186/s12893-021-01461-3

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