November 04, 2025

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Light Adjustable Lens Effective In Patients Of Cataract Surgery With History Of Laser Refractive Surgery

The second-generation Light Adjustable Lens (LAL), known as ActivShieldTM, is demonstrating remarkable outcomes in cataract patients with a history of laser refractive surgery. The findings were published in Clinical Ophthalmology.
A retrospective case series, including 33 patients (34 eyes), sheds light on the efficacy of this innovative lens in achieving optimal visual results. The study, conducted through a co-managed, open-access methodology, focused on patients with a history of laser refractive surgeries such as LASIK and/or photorefractive keratectomy (PRK). The primary outcome measures included uncorrected distance visual acuity (UDVA), spherical equivalent (SE), and residual cylinder, all evaluated during the patient’s stable, refractive postoperative examination.
Results indicate that 82.4% of patients achieved a UDVA of 20/20 or better, and an impressive 26.5% attained 20/15 or better vision. The mean SE was an incredibly low 0.01 ± 0.31 D, with 97.1% of patients within ± 0.50 D SE of plano. Additionally, the mean residual cylinder was -0.28 ± 0.32 D, and a notable 88.2% of patients were within ± 0.50 D.
This marks a significant stride in cataract surgery for individuals with a history of laser refractive procedures. The second-generation LAL's effectiveness in achieving precise refractive outcomes showcases its potential to revolutionize the field.
However, experts urge caution, emphasizing the need for further research and larger clinical trials to establish the lens's efficacy conclusively. While these preliminary findings are promising, a comprehensive understanding of the long-term effects and safety considerations is crucial.
The study not only highlights the potential of the second-generation LAL in addressing the unique needs of patients with prior laser refractive surgeries but also underscores the importance of a co-managed, open-access approach in optimizing postoperative outcomes. As ophthalmic technology continues to advance, this development offers new hope for enhanced visual outcomes in cataract surgery.
Source:
Wong, J., Folden, D., Wandling, G., Schaefer, S., Stephens, J., Boots, C., Nichols, C., Everson, M., & Johnson, R. (2023). Visual Outcomes of a Second-Generation, Enhanced UV Protected Light Adjustable Lens in Cataract Patients with Previous LASIK and/or PRK. In Clinical Ophthalmology: Vol. Volume 17 (pp. 3379–3387). Informa UK Limited. https://doi.org/10.2147/opth.s432457

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