Home OCT Device: A Useful Tool for Self-Monitoring of Neovascular Age-Related Macular Degeneration

A study published in Ophthalmology Retina suggests that the Home OCT device is a useful tool for self-monitoring of neovascular age-related macular degeneration (nAMD).

Study Overview

The study assessed the feasibility of daily Home OCT imaging among patients with nAMD. Participants meeting the ocular eligibility criteria were considered for enrollment; those who provided consent received a Notal Vision Home OCT device. Participants were instructed to scan both eyes daily. Retina specialists managed treatment according to their standard practice, without access to the Home OCT data. The presence of fluid detected by a reading center (RC) from in-office OCT scans was compared with fluid volumes measured by the Notal OCT Analyzer (NOA) on Home OCT images.

Study Findings

• Among 40 participants meeting ocular eligibility criteria, 14 (35%) initiated self-scanning.
• Planned travel (n = 7, 17.5%) and patient-reported inadequate cell reception for the upload of images (n = 5, 12.5%) were the most frequent reasons for not participating.
• Considering scans of the study eye only, the mean (standard deviation) was 6.3 (0.6) for weekly scanning frequency and 47 (17) seconds for scan duration per eye.
• Among 2304 scans, 86.5% were eligible for fluid quantification.
• All participants agreed that scanning became easier over time, and only 1 did not want to continue daily scanning.
• For 35 scan pairs judged as having fluid by in-office OCT, the NOA detected fluid on 31 scans (89%).
• For 14 scan pairs judged as having no fluid on in-office OCT, the NOA did not detect fluid on 10 scans (71%).
• Daily fluid patterns after treatment initiation varied considerably between patients.

For patients with nAMD who initiated home scanning, frequency and quality of scanning and accuracy of fluid detection were sufficient to assess the monitoring of fluid at home. Accommodations for travel and Wi-Fi connectivity could improve uptake of the Home OCT device.

Reference

Kevin J. Blinder, Claire Calhoun, Maureen G. Maguire, Adam R. Glassman, Calvin E. Mein, Darrell E. Baskin, Gabriela Vieyra, Lee M. Jampol, Moises A. Chica, Jennifer K. Sun, Daniel F. Martin, Adam R. Glassman, Roy W. Beck, Alyssa Baptista, Wesley T. Beaulieu, Claire T. Calhoun, Sharon R. Constantine, Brian B. Dale, Simone S. Dupre, Crystal A. Franklin, Sandra Galusic, Meagan Huggins, Brenda L. Hunter, Paula A. Johnson, Kristin Josic, Brittany Kelly, Danni Liu, Maureen G. Maguire, Britney Meadows, Michele Melia, Carin M. Preston, Cynthia R. Stockdale, Alice Zokruah, Jennifer K. Sun, Daniel F. Martin, Sangeeta Bhargava, Andrew J. Barkmeier, Darrell Baskin, Roy W. Beck, Barbra Blodi, Emily Chew, Frederick L. Ferris, Glenn J. Jaffe, Lee M. Jampol, Chirag D. Jhaveri, Mathew MacCumber, Lynda K. Boyd, Jarrod Wehmeier, Steve A. Schremp, Joseph M. Googe, Kristina Oliver, Justin Walsh, Julie Asher, Katie Milstead, Jeff Wheeler, Hodge A. Griffone, Home OCT Imaging for Newly Diagnosed Neovascular Age-Related Macular Degeneration: A Feasibility Study, Ophthalmology Retina, Volume 8, Issue 4, 2024, Pages 376-387, ISSN 2468-6530, https://doi.org/10.1016/j.oret.2023.10.012.

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