Researchers have found in a recent randomized, controlled human study that consumption of grapes for 16 weeks improved key markers of eye health in older adults.
This is the first human study that ooked at the impact of regular consumption of grapes on macular pigment accumulation and other biomarkers of eye health and the results reinforce earlier, preliminary studies where consuming grapes was found to protect retinal structure and function.
The study, published in the scientific journal Food & Function.
Science has shown that an aging population has a higher risk of eye disease and vision problems. Key risk factors for eye disease include 1) oxidative stress and 2) high levels of ocular advanced glycation end products (AGEs). AGEs may contribute to many eye diseases by damaging the vascular components of the retina, impairing cellular function, and causing oxidative stress. Dietary antioxidants can decrease oxidative stress and inhibit the formation of AGEs, with possible beneficial effects on the retina, such as an improvement in Macular Pigment Optical Density (MPOD). Grapes are a natural source of antioxidants and other polyphenols.
In this new study, 34 human subjects consumed either grapes (equivalent to 1 ½ cups of grapes per day) or a placebo for 16 weeks. The grape eaters showed a significant increase in MPOD, plasma antioxidant capacity, and total phenolic content compared to those on placebo. Those who didn’t consume grapes saw a significant increase in harmful AGEs, as measured in the skin.
“Our study is the first to show that grape consumption beneficially impacts eye health in humans which is very exciting, especially with a growing aging population,” said Dr. Jung Eun Kim. “Grapes are an easy, accessible fruit that studies have shown can have a beneficial impact in normal amounts of just 1 ½ cups per day.”
Reference:
Weili Hu, ORCID logo a Ruoxi Zheng, ORCID logo a Yuting Feng,a Denise Tan,ab Gregory Chan Chung-Tsing,c Xinyi Sud and Jung Eun Kim, Impacts of regular consumption of grapes on macular pigment accumulation in Singapore older adults: a randomized controlled trial, Doi: 10.1039/d3fo02105j.