Tehran, Iran: A recent study in the Archives of Iranian Medicine has linked late bedtime with the presence of premature coronary artery disease (PCAD). However, the authors stress the need for future prospective studies to elucidate the exact role of late bedtime in the development of premature coronary atherosclerosis.
Prior to the study, not much was known regarding the impact of quantity and quality of sleep on the incidence of cardiovascular disease (CVD). Farzad Masoudkabir, Tehran University of Medical Sciences, Tehran, Iran, and colleagues, therefore, aimed to investigate the possible independent association of late bedtime and premature coronary artery disease.
For this purpose, the researchers designed a cross-sectional population-based study on 30101 participants aged 20–65 years in Khuzestan Comprehensive Health Study (KCHS) between October 2016 and November 2019. They then gathered data on major risk factors of cardiovascular disease, habit history, physical activity, and sleep behavior and participants underwent blood pressure, anthropometric, and serum lipid and glucose profile measurements.
PCAD was defined as a documented history of developing obstructive coronary artery disease before 45 years in men and before 55 years in women.
Following were the study's key findings:
Of a total of 30101 participants (64.1% female, mean age: 41.7±11.7 years) included in this study, 1602 (5.3%) had PCAD.
Late bedtime was reported in 7613 participants (25.3%).
Age-sex standardized prevalence for PCAD and late bedtime were 3.62 and 27.8, respectively.
There was no significant difference regarding prevalence of PCAD between those with late bedtime (5.5%) and those with early bedtime (5.3%).
After adjustment for potential confounders, late bedtime was independently associated with PCAD (OR=1.136).
"Our study showed that going to be late was significantly associated with the presence of PCAD," wrote the authors. 'Future prospective studies should elucidate the exact role of late bedtime in developing coronary atherosclerosis prematurely."
Reference:
The study titled, "Premature Coronary Artery Disease Is More Prevalent in People Who Go to Bed Late," was published in the Archives of Iranian Medicine.
DOI: 10.34172/aim.2021.131