November 05, 2025

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Ginge-Cal Promising Material For Treatment Of Infected Root Canal When Used As Obturation Material: Study

Ginge-Cal Study

Ginge-Cal: A Promising Material for Treating Infected Root Canals

A study published in the International Journal of Dentistry suggests that Ginge-Cal is a promising material for treating infected root canals when used as obturation material.

Introduction

The tendency to use dental materials of plant origin is one of the prevailing trends in dentistry to reduce exposure to materials that could have some toxic impact in the long term. A study was done to evaluate the efficacy of calcium hydroxide combined with gingerols (Ginge-Cal) as a novel obturation material for treating infected primary teeth and decreasing the recurrence of infection.

Methodology

The study was conducted on 30 lower primary molars with infected pulp for children aged 4–8 years. The sample was randomly divided into two groups depending on the tested obturation material:

  • Ginge-Cal group
  • Metapex group

The evaluation was done by different parameters clinically and radiographically at various intervals up to 12 months.

Results

Based on chi-squared and McNamara’s test with a 5% significance level, the clinical results indicated that the Ginge-Cal group was more effective than the Metapex group in:

  • Reducing or eliminating pain after 1 week
  • Sensitivity to percussion at 3 months of follow-up
  • Purulent swelling at 6 and 9 months of follow-up
  • Fistula and tooth mobility

The radiographic results, based on the periapical and furcation area radiolucency at 12 months of follow-up, favored the Ginge-Cal group over the Metapex group. There were no statistically significant differences in pathological root resorption and periodontal space. The differences within the Ginge-Cal group were directly influenced by the time intervals in a statistically significant manner. The success percentage was 87.5% for the Ginge-Cal group and 64.3% for the Metapex group.

Ginge-Cal can be considered a promising material for treating the infected root canal when used as an obturation material for the infected root canal.

Reference

Fathi A. Qasem, Salwa M. Awad, Rizk A. Elagamy, "Effectiveness of Calcium Hydroxide and Gingerols Mixture as a Novel Obturation Material for Infected Root in Primary Teeth: A Randomized Clinical Trial", International Journal of Dentistry, vol. 2024, Article ID 5528260, 10 pages, 2024. https://doi.org/10.1155/2024/5528260

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