Tea consumption might be closely related to non-malignant digestive diseases including gastroesphageal reflux disease.Nevertheless, this correlation remains inadequately comprehended.
Gastroesophageal reflux disease (GERD) is one of the most common digestive system diseases, which is associated with lifestyle and dietary factors. The main mechanism involved in GERD is affected by demographics, lifestyles, and dietary factors.
Previous studies have mentioned that tea consumption may be associated with symptoms like heartburn and reflux. Some studies have reported its association with GERD. More data is needed to clarify this association.
A recent study published in Clinical Nutrition ESPEN concluded that tea consumption increases the likelihood of gastroesophageal reflux disease (GERD).
This study elucidated the connection between tea consumption and non-malignant digestive diseases, which has not been fully understood. Researchers employed a Mendelian randomization approach to study tea's impact on specific digestive disorders. Genetic data from the UK Biobank, including 447,485 participants, was used to investigate this relationship. They chose a gene-wide association study with no sample overlap and UKB as a data source for all outcomes. The primary analytical method utilized was inverse variance weighting, and multiple analytical models were employed to enhance the analysis's reliability and ensure robust results.
This study found that tea consumption was linked to an elevated susceptibility to gastroesophageal reflux disease (GERD). However, there was a lack of substantial evidence suggesting an association between tea intake and diseases like Crohn's disease (CD), ulcerative colitis (UC), or non-alcoholic fatty liver disease (NAFLD).
They concluded that excessive tea consumption may heighten the likelihood of GERD. The study highlights the importance of dietary pattern modifications for GERD patients.
These results hold potential significance in guiding dietary pattern modifications for individuals with GERD. Furthermore, there may be value in implementing GERD monitoring and preventive measures in populations with elevated tea consumption.
Reference:
Sun, Qi, et al. "The Association Between Tea Consumption and Non-malignant Digestive System Diseases: a Mendelian Randomized Study." Clinical Nutrition ESPEN, vol. 60, 2024, pp. 327-332.
DOI: https://doi.org/10.1016/j.clnesp.2024.02.012