November 05, 2025

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Disinhibited Eating, Anxiety And Depression Noted In Youth Genetically Predisposed To Type 2 Diabetes: Study

USA: A recent study showed that youth with a parent with type 2 diabetes (P-T2D) reported higher symptoms of depression and anxiety and disinhibited eating behaviors versus those without P-T2D. The study appears in the journal Pediatric Diabetes.
Previous studies have reported a high risk of developing type 2 diabetes aming children whose parents have type 2 diabetes. However, it is not known if youth with P-T2D reported greater psychological and behavioral symptoms compared to those without a P-T2D. To find more about the topic, Taylor N. Swanson, Metis Foundation, San Antonio, Texas, USA, and colleagues aimed to compare youth with and without a P-T2D on symptoms of negative affect and disinhibited-eating.
For this purpose, 932 youth (13.3 ± 2.6 years; BMIz 1.06 ± 1.06; 67.8% female; 53.6% people of color; 10.7% with a P-T2D) completed questionnaires of anxiety and depressive symptoms, eating in the absence of hunger, and emotional-eating. Loss-of-control (LOC)-eating was assessed by interview.
In two separate subsamples, the researchers explored energy intake using laboratory test meals simulating eating in the absence of hunger and LOC-eating, respectively.
The study revealed the following findings:
Adjusting for all covariates including adiposity and IR, compared to youth without a P-T2D, youth with a P-T2D reported more anxiety and depression symptoms, greater eating in the absence of hunger, and emotional-eating.
No significant differences were found for LOC-eating, or in exploratory analyses of energy intake for either test meal.
"Self-reported negative affect and disinhibited-eating may be higher among youth with P-T2D compared to those without P-T2D," the authors wrote. "Prospective studies should examine, among those with a P-T2D, what role such symptoms may play for their subsequent risk for T2D."
Reference:
The study titled, "A comparison of negative affect and disinhibited eating between children with and without parents with type 2 diabetes," is published in the journal Pediatric Diabetes.
DOI: https://onlinelibrary.wiley.com/doi/10.1111/pedi.13286

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