November 03, 2025

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Consumption Of Fresh Vegetables Has Potential Benefit Of Improving EGFR Among Elderly

Diet rich in Fresh vegetables has potential benefit of improving eGFR among elderly suggests a new study published in the BMC Nephrology.
This study aimed to investigate the relationship between the consumption of fresh and salt-preserved vegetables and the estimated glomerular filtration rate (eGFR), which requires further research.
The prevalence of chronic kidney disease (CKD) generally increases with age owing to nephron loss and a decline in the glomerular filtration rate (GFR). The estimated GFR (eGFR) assumes a widely recognized role as a marker that plays a pivotal role in evaluating overall kidney health and diagnosing various renal disorders.

For this purpose, the data of those subjects who participated in the 2011–2012 and 2014 surveys of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) and had biomarker data were selected. Fresh and salt-preserved vegetable consumptions were assessed at each wave. eGFR was assessed using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation based on plasma creatinine. Furthermore, a linear mixed model was used to evaluate associations between fresh/salt-preserved vegetables and eGFR.
Results
The results indicated that the median baseline and follow-up eGFRs were 72.47 mL/min/1.73 m² and 70.26 mL/min/1.73 m², respectively. After applying adjusted linear mixed model analysis to the data, the results revealed that compared to almost daily intake, occasional consumption of fresh vegetables was associated with a lower eGFR (β=-2.23, 95% CI: -4.23, -0.23). Moreover, rare or no consumption of salt-preserved vegetables was associated with a higher eGFR (β = 1.87, 95% CI: 0.12, 3.63) compared to individuals who consumed salt-preserved vegetables daily.
Fresh vegetable consumption was direct, whereas intake of salt-preserved vegetables was inversely associated with eGFR among the oldest subjects, supporting the potential benefits of diet-rich fresh vegetables for improving eGFR.
Reference:
Zheng, H., Li, H., Pan, L. et al. Association of fresh vegetable and salt-preserved vegetable consumptions with estimated glomerular filtration rate. BMC Nephrol 24, 369 (2023). https://doi.org/10.1186/s12882-023-03353-5
Keywords:
Diet, rich, Fresh, vegetable, potential, benefit, of, improving, eGFR, among, elderly, BMC Neph8rology, Zheng, H., Li, H., Pan, L

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